Experimental Study on Relationship of Applied Power And Feeding Rate on Production of Polyurethane Nanofibre
In this work, a polymer of polyurethane (PU) was electrospun for 1 hour to create a scaffold under different conditions. A 3x3 general full factorial in a completely randomised design using three levels of two factors: power (W= 20, 22 and 25 Watts) and feeding rate (V=1.00, 1.25 and 1.50 ml/h) was used to assess the response pattern and to determine the combined effect of independent variables. The main effects for power (W) and feeding rate (V) and the power (W)*feeding rate (V) interaction were statistically significant.
Key words: Electrospinning, Polyurethane, Nanofibre, Statistical Analysis.
Yoo, H.S., Kim, T.G., Park, T.G., “Surface- functionalized electrospun nanofibers for tissue engineering and drug delivery”, Adv Drug Deliv Rev, 61: 1033–1042, (2009).
Schreuder-Gibson, H.L., Gibson, P., Seneca, K., Sennett, M., Walker, J., Yeomans, W., et al., “Protective textile materials based on electrospun nanofibers”, J Adv Mat, 34(3): 44–55, (2002).
Wang, X.Y., Lee, S.H., Drew. C., Senecal, K.J., Kumar, J., Samuelson, L.A., “Highly sensitive optical sensors using electrospun polymeric nanofibrous membranes”, Mat Res Soc Symp Pro, 708:397– 402, (2002).
Ondarcuhu, T. and Joachim, C., “Drawing a single nanofibre over hundreds of microns”, Europhys Lett, 42(2): 215–220, (1998).
Ma, P.X. and Zhang, R., “Synthetic nano-scale fibrous extracellular matrix”, J Biomed Mat Res, 46 : 60–72, (1999).
Deitzel, J.M., Kleinmeyer, J., Hirvonen, J.K., Beck, T.N.C., electrospun poly(ethylene oxide) fibers”, Polymer, 42: 8163–8170, (2001a). deposition of
Bhardwaj, N. and Kundu, S.C., “Electrospinning: A Biotechnology Advances, 28: 325–347, (2010). technique”,
Ramanathan, K., Bangar, M.A., Yun, M., Chen, W., Myung, N.V., Mulchandani, A., “Bioaffinity sensing conducting-polymer nanowire” J Am Chem Soc, 127: 496–507, (2005). functionalized
Ramakrishna, S., Fujihara, K., Teo, W.E., Yong, T., Ma, Z., Ramaseshan, R., “Electrospun nanofibers: solving global issues”, Mater Today , 9: 40–50, (2006).
Figeys, D. and Pinto, D., “Lab-on-a-chip: a revolution in biological and medical sciences—a look at some of the basic concepts and novel components used to construct prototype devices”, Anal Chem., 72: 330A–335A, (2000).
Friess, W., “Collagen biomaterial for drug delivery”, Eur J Pharm Biopharm, 45: 113–136, (1998).
Li, W.J., Laurencin CT, Caterson EJ, Tuan RS, Ko FK., “Electrospun nanofibrous structure: a novel scaffold for tissue engineering”, J Biomed Mater Res, 60: 613–621, (2002).
He, W., Horn, S.W., Hussain, M.D., “Improved bioavailability of orally administered mifepristone from PLGA nanoparticles”, Int J Pharm, 334: 173–178, (2007).
Liang, D., Hsiao, B.S., Chu, B., “Functional electrospun nanofibrous scaffolds for biomedical applications”, Adv Drug Deliv Rev, 59: 1392– 1412, (2007). Po wer (W ) 2 0 2 2 2 5